Program | Antimic

Preliminary program

16:00	Welcome
16:20	Cesar de la Fuente, University of Pennsylvania, United States Accelerating antibiotic discovery with AI Abstract
17:20	Sylvie Rebuffat, Muséum national d'Histoire naturelle, France The continuous story of bacteriocins until emerging origins and methods for discovery Abstract
18:20	Welcome reception

Session 1: Innovative tools for screening and prediction Moderators: Rozenn Ravallec, Université de Lille, France and Laurent Bazinet, Université Laval, Canada
8:30	Wananit Wimuttisuk, National Science and Technology Development Agency (NSTDA), Pathum Thani,Thailand Metabolomic variation along the gastrointestinal tract of shrimp with white feces syndrome Abstract
8:50	Laurent Bazinet, Université Laval, Quebec, Canada Combining statistical, machine learning and experimental approaches for screening of novel antimicrobial peptides from complex hydrolysates Abstract
9:10	Séverine Zirah, Muséum national d'Histoire naturelle, Paris, France Microcin diversity and role in competitive interactions in poultry microbiota Abstract
9:30	Yesmine Sahnoun, Université Laval, Quebec, Canada Rapid bioinformatics and machine learning based identification of respiratory bacterial pathogens to assist antimicrobial stewardship Abstract
9:50	Coffee break and poster session
Session 2: Discovery and design of new antimicrobials Moderators: Ismail Fliss and Lucie Beaulieu, Université Laval, Canada
10:20	Anna Aris, Institute of Agrifood Research and Technology, Caldes de Montbui, Spain Concatenating Bacteriocins as an antibiotic alternative for ruminants and aquaculture Abstract
10:40	Kitiya Vongkamjan Aurand, Kasetsart University, Bangkok, Thailand Isolation and characterization of novel broad-host range Vibrio phages for phage-based biocontrol formulation for the treatment of early mortality syndrome in shrimps Abstract
11:00	Éric Biron, Université Laval, Quebec, Canada The lipopeptide brevibacillin: A promising scaffold for the development of antimicrobials with tunable pharmacological properties and spectra of activity Abstract
11:20	Françoise Coucheney, Université de Lille, Lille, France Bacteriocins from Lacticaseibacillusparacasei CNCM I-5369: anti-Escherichia coli activity, original export system, potential medical application Abstract
11:40	Lucie Beaulieu, Université Laval, Quebec, Canada Screening of algal extracts antimicrobial activity for cheese preservation and characterization of active extracts Abstract
12:00	Mohammed Rhouma, Université de Montréal, Saint-Hyacinthe, Canada First steps toward the discovery of a new generation of veterinary-specific tetracyclines: The case of oxytetracycline degradation products Abstract
12:20	Lunch

Session 3: Microbiome engineering Moderators: Séverine Zirah, MNHN, France and Frédéric Borges, Université de Lorraine, France
14:00	Frédéric Borges, Université de Lorraine, Nancy, France Top-down strategies for engineering microbial communities with antimicrobial properties Abstract
14:30	Ismail Fliss, Université Laval, Quebec, Canada Harnessing natural antimicrobial peptides to tackle Clostridium in the dairy sector: Breaking the transmission cycle from silage to cheese Abstract
Session 4: Antibiotic resistance and emerging alternatives Moderators: Simon Heilbronner, LMU Munich, Germany and Carmen Torres, University of La Rioja, Spain
14:50	Simon Heilbronner, LMU Munich, Munich, Germany Feast or famine: Nutrient sharing affects S. aureus growth in the nasal ecosystem Astract
15:20	Margaret Crumlish, University of Stirling, Stirling, United Kingdom Tracking Resistance: Phenotypic and Genomic Insights into Antimicrobial Resistance in Aquatic Bacterial Pathogens in Vietnam Abstract
15:40	Nguyen Giang Thu Lan, Asian Institute of Technology, Pathum Thani, Thailand Reducing antibiotic use in tilapia aquaculture through scalable vaccination strategies Abstract
16:00	Axel Pitard, Université de La Rochelle, La Rochelle, France Plant-Derived Antibacterials Against Multidrug-Resistant Pathogens: From Bactericidal Activity to Synergistic Combinations Abstract
16:20	Poster session

8:30 am – 4:30 pm Workshop for students only

Approches intégratives et intelligence artificielle pour la recherche d'antimicrobiens

Animateurs: Séverine Zirah, Muséum national d'Histoire naturelle, Paris, France et

Vivien Conti, Sorbonne Cluster for Artificial Intelligence, Paris, France

Cet atelier proposera une expérience immersive conçue pour familiariser les participants avec la diversité des ensembles de données « omiques » ainsi qu’avec les principes de classification et d’apprentissage automatique appliqués à la recherche sur les antimicrobiens.

Après une introduction aux méthodes multi-omiques ainsi qu'aux méthodes de classification et d'apprentissage automatique, un atelier pratique d'IA permettra de prédire l'activité antibactérienne de peptides à partir de leur séquence en acides aminés.

Cet atelier est organisé dans le cadre du programme de recherche international AviBiocin2 financé par le Centre de Recherches pour le Développement International (CRDI) et a bénéficié de bourses de l'Association de Chimiothérapie Anti-Infectieuse (ACAI).