Session 1: Innovative tools for screening and prediction Moderators:
8:30
Wananit Wimuttisuk, National Science and Technology Development Agency (NSTDA), Pathum Thani,Thailand Metabolomic variation along the gastrointestinal tract of shrimp with white feces syndrome
Session 2: Discovery and design of new antimicrobials Moderators:
10:40
Anna Aris, Institute of Agrifood Research and Technology, Caldes de Montbui, Spain Concatenating Bacteriocins as an antibiotic alternative for ruminants and aquaculture
Kitiya Vongkamjan Aurand, Kasetsart University, Bangkok, Thailand Isolation and characterization of novel broad-host range Vibrio phages for phage-based biocontrol formulation for the treatment of early mortality syndrome in shrimps
Éric Biron, Université Laval, Quebec, Canada The lipopeptide brevibacillin: A promising scaffold for the development of antimicrobials with tunable pharmacological properties and spectra of activity
Françoise Coucheney, Université de Lille, Lille, France Bacteriocins from Lacticaseibacillusparacasei CNCM I-5369: anti-Escherichia coli activity, original export system, potential medical application
Lucie Beaulieu, Université Laval, Quebec, Canada Screening of algal extracts antimicrobial activity for cheese preservation and characterization of active extracts
Mohammed Rhouma, Université de Montréal, Saint-Hyacinthe, Canada First steps toward the discovery of a new generation of veterinary-specific tetracyclines: The case of oxytetracycline degradation products
Margaret Crumlish, University of Stirling, Stirling, United Kingdom Tracking Resistance: Phenotypic and Genomic Insights into Antimicrobial Resistance in Aquatic Bacterial Pathogens in Vietnam
Nguyen Giang Thu Lan, Asian Institute of Technology, Pathum Thani, Thailand Reducing antibiotic use in tilapia aquaculture through scalable vaccination strategies
Session 4: Antibiotic resistance and emerging alternatives (to be continued) Moderators:
8:30
Mario Pablo Estrada, Center for Genetic Engineering and Biotechnology (CIGB),Havana, Cuba Fighting antimicrobial resistance in aquaculture: new findings on PACAP antibacterial activity support host defense peptides as alternatives in aquaculture
Shafiq Ur Rehman, University of the Punjab, Lahore, Pakistan Assessment of Bacteriophage cocktails (Sal-Pak-1 and Sal-Pak-2) Efficacy against Salmonella Gallinarum Infection in Broiler Chicken
Warangkhana Songsungthong, National Science and Technology Development Agency (NSTDA), Pathum Thani, Thailand Universal Vibrio antigens stimulate shrimp immunity and protect shrimp against pathogenic Vibrio infection
Axel Pitard, Université de La Rochelle, La Rochelle, France Plant-Derived Antibacterials Against Multidrug-Resistant Pathogens: From Bactericidal Activity to Synergistic Combinations
Session 5: Emerging challenges for AMR innovations Moderators:
9:50
Sunday O. Ochai, International Centre for Antimicrobial Resistance Solutions (ICARS), Copenhagen, Danmark AMR in a Changing Environment: Bridging Evidence, Policy, and Practice gaps at the Climate - AMR Nexus in Low- and Middle- Income countries
Integrative approaches and artificial intelligence for antimicrobial research
Facilitator: Séverine Zirah, National Museum of Natural History, Paris, France
This workshop will offer an immersive experience designed to familiarise participants with the diversity of “omics” datasets, as well as with the principles of classification and machine learning as applied to antimicrobial research.
Following an introduction to multi-omic methods, as well as classification and machine learning methods, a hands-on computer-based workshop will use a dataset compiled from a collection of antibiotic-resistant Enterobacteriaceae strains (1,2). The joint analysis of phenotypic data (antimicrobial activities of bacteriocins) and genomic data will aim to generate tools for predicting the sensitivity of strains to bacteriocins, followed by an assessment of their relevance.
References: 1. Telhig S, Pham NP, Ben Said L, Rebuffat S, Ouellette M, Zirah S, Fliss I. Exploring the genetic basis of natural resistance to microcins. Microb Genom. 2024,10:001156. doi: 10.1099/mgen.0.001156. 2. Telhig S, Ben Said L, Torres C, Rebuffat S, Zirah S, Fliss I. Evaluating the Potential and Synergetic Effects of Microcins against Multidrug-Resistant Enterobacteriaceae. Microbiol Spectr. 2022, 10:e0275221. doi: 10.1128/spectrum.02752-21.